Dictionary Definition

arteriosclerosis n : sclerosis of the arterial walls [syn: arterial sclerosis, hardening of the arteries, induration of the arteries, coronary-artery disease] [also: arterioscleroses (pl)]

User Contributed Dictionary

English

Pronunciation

a Canada

Noun

Translations

hardening, narrowing or loss of elasticity in arteries or blood vessel
  • Albanian: arteriosklerozë
  • French: artériosclérose
  • German: Arteriosklerose

Related terms

Extensive Definition

Arteriosclerosis refers to a hardening of medium and large arteries. The most common form of arteriosclerosis is atherosclerosis.

Etymology

The following terms are similar, yet distinct, in both spelling and meaning, and can be easily confused: arteriosclerosis, arteriolosclerosis, and atherosclerosis. Arteriosclerosis is a general term describing any hardening (and loss of elasticity) of medium or large arteries (from the Greek Arterio, meaning artery, and sclerosis, meaning hardening), arteriolosclerosis is any hardening (and loss of elasticity) of arterioles (small arteries), atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. Therefore, atherosclerosis is a form of arteriosclerosis.

Types

  • Atherosclerosis is the most common form of arteriosclerosis. In atherosclerosis, thickening of the intima with plaques that can contain lipid-laden macrophages ("foam cells"). The plaques contain free lipid (cholesterol, etc.) and are prone to calcification and ulceration.
  • Arteriosclerosis obliterans is typically seen in medium and large arteries of the lower extremity. Characterized by fibrosis of the intima and calcification of the media. The lumen of the vessel may be obliterated or markedly narrowed.
  • Medial calcific sclerosis (Monckeberg’s calcific sclerosis) is seen mostly in the elderly, commonly in arteries of the thyroid and uterus. Characterized by calcification of the internal elastic lamina but without thickening of the intima or narrowing of the vessel lumen. A similar form of an intramural calcification, presenting the picture of an early phase of arteriosclerosis, appears to be induced by a number of drugs that have an antiproliferative mechanism of action (Rainer Liedtke 2008).
  • Hyaline arteriolosclerosis refers to thickening of the walls of arterioles by the deposition of hyaline material. Often seen in kidney pathology.
arteriosclerosis in Spanish: Arteriosclerosis

Synonyms, Antonyms and Related Words

angina, angina pectoris, aortic insufficiency, aortic stenosis, apoplectic stroke, apoplexy, arrhythmia, atherosclerosis, atrial fibrillation, auricular fibrillation, beriberi heart, calcification, callusing, cardiac arrest, cardiac insufficiency, cardiac shock, cardiac stenosis, cardiac thrombosis, carditis, case hardening, concretion, congenital heart disease, cor biloculare, cor juvenum, cor triatriatum, cornification, coronary, coronary insufficiency, coronary thrombosis, crystallization, diastolic hypertension, encased heart, endocarditis, extrasystole, fatty heart, fibroid heart, firming, flask-shaped heart, fossilization, frosted heart, granulation, hairy heart, hardening, heart attack, heart block, heart condition, heart disease, heart failure, high blood pressure, hornification, hypertension, hypertensive heart disease, induration, ischemic heart disease, lapidification, lithification, mitral insufficiency, mitral stenosis, myocardial infarction, myocardial insufficiency, myocarditis, myovascular insufficiency, ossification, ox heart, palpitation, paralytic stroke, paroxysmal tachycardia, pericarditis, petrifaction, petrification, pile, premature beat, pseudoaortic insufficiency, pulmonary insufficiency, pulmonary stenosis, rheumatic heart disease, round heart, sclerosis, setting, solidification, steeling, stiffening, stony heart, stroke, tachycardia, tempering, thrombosis, toughening, tricuspid insufficiency, tricuspid stenosis, turtle heart, varicose veins, varix, ventricular fibrillation, vitrifaction, vitrification
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